NAD+ vs. FAD: Key Differences and Roles in Cellular Energy Production

• Boosts Cellular Energy Production: Enhances mitochondrial function to support sustained energy levels and combat fatigue.
• Supports Brain Function: Improves cognitive clarity, memory retention, and neurological health by promoting cellular repair.
• Enhances DNA Repair: Aids in maintaining genetic stability, reducing oxidative stress, and slowing age-related cellular decline.
• Reduces Inflammation: Helps regulate immune responses to lower chronic inflammation and promote long-term wellness.
• Supports Metabolic Health: Improves insulin sensitivity and helps regulate metabolic processes for better weight and glucose control.

• Aids in Energy Metabolism: Promotes the breakdown of carbohydrates, fats, and proteins to sustain bodily energy needs.
• Supports Antioxidant Defense: Helps neutralize free radicals and protect cells from oxidative damage.
• Promotes Red Blood Cell Formation: Plays a key role in maintaining healthy oxygen transport and reducing anemia risk.
• Enhances Nervous System Function: Supports neurotransmitter production for balanced mood and cognitive stability.
• Supports Skin and Eye Health: Contributes to tissue repair, reducing dryness, irritation, and age-related degeneration.

• Method of Administration: NAD+ is typically administered via intravenous (IV) infusion, subcutaneous injection, or oral supplements.
• Typical Dosage: IV infusions commonly range from 250 mg to 750 mg per session, while oral supplements may provide 300–600 mg daily.
• Optimal Timing: NAD+ infusions are often given in the morning or early afternoon to support energy production, while oral supplements are best taken with food.
• Safe Combinations: NAD+ pairs well with glutathione injections for enhanced detoxification and B-complex vitamins to support cellular metabolism.

• Method of Administration: FAD is primarily taken as an oral supplement but can also be included in IV therapy formulations.
• Typical Dosage: A standard daily dosage of FAD supplements ranges from 10 mg to 50 mg, depending on individual needs.
• Optimal Timing: FAD is best taken in the morning with food to optimize absorption and support energy metabolism throughout the day.
• Safe Combinations: FAD can be safely combined with CoQ10 supplements for mitochondrial support and NMN for increased cellular energy production.

• Onset Time: NAD+ supplementation typically begins working within 30 to 60 minutes, depending on the delivery method (e.g., IV vs. oral).
• Duration of Effects: The therapeutic effects of NAD+ last between 4 to 8 hours after administration, with IV forms providing longer-lasting benefits.
• Immediate vs. Cumulative Effects: Some effects, like increased energy and mental clarity, may be noticed immediately, but long-term benefits (e.g., improved cellular repair and anti-aging effects) accumulate over weeks to months.
• When to Expect Noticeable Results: Many patients report noticeable improvements in cognitive function and energy levels within the first few doses, with more substantial results seen after consistent use over several weeks.

• Onset Time: FAD generally starts working within 60 to 90 minutes, as it must be converted into its active form to exert effects.
• Duration of Effects: The benefits of FAD last approximately 6 to 12 hours, depending on individual metabolism and dosage.
• Immediate vs. Cumulative Effects: Some users experience an initial boost in energy and metabolism, but full cellular and enzymatic support effects develop gradually with continued use.
• When to Expect Noticeable Results: Most users begin to notice enhanced metabolic and mitochondrial function within a few days, with more pronounced improvements appearing after several weeks of supplementation.

Common Side Effects (Mild to Moderate):

• Mild headache
• Nausea
• Flushing sensation

Rare but Serious Side Effects (Moderate to Severe):

• Dizziness or lightheadedness
• Increased heart rate
• Allergic reaction (itching, swelling)

Safety Summary: NAD+ supplements and IV infusions are generally well-tolerated, with most side effects being mild and temporary. However, high doses may cause discomfort, particularly flushing and nausea.

When to Seek Medical Attention: Immediate medical help is necessary if severe dizziness, rapid heartbeat, or signs of an allergic reaction occur.

Drug Interactions: Potential interactions with blood pressure medications and certain metabolic enhancers should be considered before use.

Common Side Effects (Mild to Moderate):

• Mild gastrointestinal discomfort
• Fatigue
• Dry mouth

Rare but Serious Side Effects (Moderate to Severe):

• Difficulty breathing
• Severe abdominal pain
• Muscle weakness

Safety Summary: FAD supplementation is generally safe, with most adverse effects being short-term and mild. Long-term risks are minimal when recommended dosages are followed.

When to Seek Medical Attention: Seek medical care if experiencing severe abdominal pain, difficulty breathing, or persistent muscle weakness.

Drug Interactions: May interact with medications affecting mitochondrial function or metabolic pathways; consult a healthcare provider before combining.

NAD+ is best suited for individuals looking to enhance cellular energy production, support brain function, and promote healthy aging.

• Adults over 30 experiencing fatigue, brain fog, or decreased energy levels
• Individuals managing age-related cognitive decline or neurodegenerative conditions
• Those recovering from metabolic stress, chronic inflammation, or prolonged illness

FAD is ideal for individuals needing robust enzymatic support for metabolism and oxidative stress regulation.

• People with metabolic disorders requiring enhanced energy conversion and nutrient processing
• Individuals with chronic oxidative stress or mitochondrial dysfunction seeking additional cellular protection
• Athletes or highly active individuals needing optimized enzymatic activity for endurance and muscle recovery