Cialis and Viagra are often the go-to meds for ED. These PDE5 inhibitors act as a first line of treatment for men against ED.
But, about 30 – 35% of men don’t respond to traditional ED drugs.
Trimix may offer an alternative to oral ED meds when they don’t bring a response.
One study has shown that 89% of men taking a Trimix injection achieved an erection strong enough for intercourse even with other underlying health conditions (though the impact was less significant).Other studies indicate a highly significant increase in sexual satisfaction from men using penile injections.
Table of Contents
What is Trimix?
Trimix is an intracavernosal penile injection therapy combining alprostadil, phentolamine, and papaverine. It is typically prescribed for treating erectile dysfunction (ED), particularly in men who do not respond to oral medications.
In some clinical trials, 89% of men achieved erections satisfactory for intercourse. Trimix maintains a high response rate even among men who were unresponsive to oral ED medications.
The three medications in Trimix:
- Papaverine relaxes smooth muscles in blood vessels and dilates them to increase blood flow into the penis.
- Phentolamine is another medication that relaxes smooth muscles in blood vessels and dilates them to increase blood flow into the penis.
- Alprostadil or prostaglandin E1, relaxes the smooth muscle that makes up the structure of the penis and dilates blood vessels supplying blood to the penis, which stiffens the penis for an erection.
Trimix is available by prescription only and is typically prepared by a compounding pharmacy.
What is a penile injection?
When you want to deliver potential drug therapy directly to the source, a penile injection does the job. Penile injections are given into the side of the penis using a short, very fine needle.
The medication is quickly injected into a cavernous space on the side of the penis, and pressure is applied for at least 5 minutes.
In some cases, penile injections begin to work in 10 to 15 minutes, and their effects last for 30 to 60 minutes.
Aggregate studies show an efficacy of 54% – 100% for penile injections.
It can be intimidating at first, but research shows that many men preferred penile injections over some oral tablets.
Some men that choose penile injections say that they have a better erection with penile injections than on oral medications.
Side effect profile, contraindications to oral meds, ease of use, and lack of systemic side effects are a few reasons why a patient would prefer penile injections to oral medication.
Take a deep dive into Trimix for more info on how it may address ED.
How often can you use Trimix injections?
Follow your doctor’s dosing instructions, but generally, Trimix injections should not be used more than once in 24 hours, more than two days in a row, or more than two or three times in a week.
What is Trimix gel?
Trimix gels contain the same active ingredients as Trimix injections, papervine, phentolamine, and alprostadil. Trimix gels have been available in two forms: a topical and an intraurethral gel.
According to one study, while Trimix topical gel is more stable and easier to use than Trimix injections, however the results are frequently unsatisfactory thought to be due to poor absorption.
Intraurethral Trimix gel is applied to the top of the penis at the urethral opening.
In a study that involved a group of men with ED, after using intraurethral gel, 40% of men had an erection firm enough for penetrative sex.
The authors suggest that more research and larger studies are needed.
What is the average cost of Trimix gel?
Pricing varies depending on where you decide to purchase.
Trimix gel is only available by prescription from a compounding pharmacy. Speak to your doctor about getting a prescription.
Trimix intraurethral powder is mixed with a gel. An adaptor piece is attached to the end of the syringe. The adaptor is held firmly against the urethral opening, and the medication is pushed into the urethra.
Gently pinch the tip of the urethra and massage the glands around the end of the penis.
How long does it take for Trimix gel to work?
While Trimix gels may not be absorbed in the body well enough, Trimix injections may have better bioavailability.
Like Trimix injections, Trimix gels are expected to work in about 10 minutes and last for about 30 minutes.
Make Your Choice
Trimix’s versatility and potential effectiveness offers a promising alternative to traditional oral ED medications.
Speak with your doctor to get more clarity and context for your unique situation.
Frequently Asked Questions
How often can Trimix gel be used?
The frequency of Trimix gel use depends on individual needs and healthcare provider recommendations.
Typically, Trimix gel is applied as needed, with dosage and frequency determined based on factors such as the severity of ED and individual response to the medication.
It’s important to follow healthcare provider instructions carefully and not exceed the recommended dosage or frequency of use.
How long does Trimix gel keep you hard?
The duration of Trimix gel can vary among individuals and depends on factors such as dosage, individual response, and level of sexual stimulation.
Follow healthcare provider instructions regarding dosage and timing to optimize the duration of the erection and minimize the risk of complications such as priapism.
How can I make Trimix work better?
To optimize the effectiveness of Trimix, it’s important to follow healthcare provider instructions carefully. This includes ensuring proper application technique, dosage, and timing.
Additionally, maintaining overall health through regular exercise, a balanced diet, and managing underlying health conditions can support the effectiveness of Trimix gel treatment.
Open communication with a healthcare provider about any concerns or difficulties with Trimix gel can also help tailor treatment for better results.
Does Trimix gel have to be refrigerated?
Trimix gel may need to be refrigerated depending on the specific formulation and storage instructions provided by the manufacturer or healthcare provider.
It’s essential to follow proper storage guidelines to maintain the stability and effectiveness of the medication.
Consult with a healthcare provider or pharmacist for specific guidance on how to store Trimix gel properly.
